Actos
Actos questions and answers
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Q: Does Actos increase depression or react with antidepressants?
Even though my doctor has increased my antidepressants twice since I started Actos, I have noticed a marked increase in my depression symptoms since starting the Actos. I've been on Actos about three months.
A: The cause of the depression is the same as the cause of your diabetes. Trust me, I've been there. It all has to do with poor health due to improper diet and lack of physical activity. I dug my way out of deep, dark depression, and fought my way off the diabetes medication. I've been totally drug free since December 13, 2007. I strongly urge you to learn more....
Q: What is the difference between Actos and Avandia. Does Actos have the same side effects as Avandia?
Lately Avandia has been associated with heart failure according to New England Medical Journal. Actos is also being associated with this risk being a similar salt to Avandia. Does anyone know the similarities and differences between the two drugs
A: I disagree with the above poster. I think this is a battle for market share.
The New England Journal of Medicine was really taken to task for publishing the Avandia article. Read the article for yourself. Also read the scathing response in the Lancet, an equally well-respected British medical journal.
Then talk to your doctor about how this (old) data applies to your particular situation. As with all meds, you must ask whether the benefits outweigh the risks. Often they really do.
What bugs me about this one is the way it was driven, funded, published and hyped.
Q: Have you switched from Metformin to Actos?
I've been on Metformin for several years, & think I'm getting side-effects. I asked the doctor to switch me to something else, & he prescribed Actos. What's your experience?
A: I took Metformin and my stomach suffered! I feel your pain.
I started taking glipizide, which worked great for a while, but my doctor thought adding another drug would help so she prescribed actos.
Actos is awful!!! It did not help me with bg hardly at all, it gave me joint pain and I also started gaining weight (keeping in mind that my diet has been the same and I do excercise).
Keep in mind that every body is different, it might work great for you.
Q: Has anyone used the byetta pin and actos plus and does it work?
My dr recently changed my medicine and when I run out of what I have I have to start with the new prescription and was just wondering if anyone had anything good or bad to say about it.I hate trying new meds
A: I have just begun to take BYETTA but cannot get past the feeling nauseous part. When I do take it, it seems to kill my appetite...plus for weight loss!
Q: how does actos help in controlling my diabetes?
I just need some info on the tablet that was added to my other meds that i was already taking.
A: Pioglitazone is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.
Pioglitazone is used either alone or in combination with other anti-diabetic medications (e.g., metformin, sulfonylureas, insulin).
And now the rest of the story:
The "glitazone" diabetes drugs Actos and Avandia may double or triple the risk of broken bones after a year or two of use.
The finding comes from Swiss researchers who analyzed 12 years of data on U.K. diabetes patients. They compared the 1,020 patients who suffered some kind of fracture to 3,728 matched patients who did not break any bones.
Over the course of the study, most of the patients took several diabetes drugs. But those who refilled their Actos or Avandia prescriptions eight times or more -- about 12 to 18 months of use -- had nearly twice the fracture risk of other patients.
And those who refilled their Actos or Avandia prescriptions 15 times or more -- two or more years of treatment -- nearly tripled their risk of fracture, found Christophe R. Meier, PhD, head of pharmacoepidemiology research at University Hospital Basel, Switzerland, and colleagues.
Also related heart disease>>>>
Q: Has anyone had success using Byetta along with Actos?
I have been off and on oral medications for Type 2 diabetes.... I have just now gotten back into the groove and now I am currently on Actos and Byetta 5....(luckily with no digesttive problems!) Has anyone out there had any succes with this combination?
A: I'm on byetta 10 an metformin my BS is 80 to120 its working great for me.Also lost 15 lbs an still loosing
Q: Beyond swelling of extremities, are there any serious consequences of taking actos and glyburide/metformin?
My doctor says I should tough it out. Is there no more serious effect from the swelling? I don't want to put up with this, and find out in a year from now that I have to have my foot cut off!
A: Swelling of the feet will not cause you to have a foot cut off. Going barefoot, cutting your foot and getting an infection that won't heal and turns into gangrene may cause you to have your foot cut off. Try wearing support socks to reduce the swelling and stay as active as possible so you keep a good supply of blood going to your feet. If your doctor is concerned about the swelling he will probably order a diuretic but it doesn't sound like he sees a problem at this time.
Q: Can anyone tell me what the drug Actos actually does?
I know it's used for diabetic, pre-diabetic, insulin-resistant and polycystic ovarian syndromes, but how does it improve the body's internal functions?
A: Actos helps to make your body more sensitive to the insulin that your body already has. It helps decrease insulin resistance. Insulin resistance makes it harder to lose weight and may contribute to elevated triglyceride levels in the body. Liver functions tests must be checked when you take Actos.
Q: Anyone here have or know someone who is diabetic that takes the med: Actos?
I just want to know if you/they have experienced any weight gain. My doctor says that it doesn't cause weight gain. But I have heard from many who use the drug that it does. I was on Metformin, which she took me off and put me on Actos. I have lost 15 pounds prior to using Actos with diet and exercise. Just want to know more I suppose...thanks.
A: I was on Actos for over a year and what my doctor told me is that Actos can make it harder to lose weight and find they gain weight. I gained a bit but nothing big. I thankfully was able to switch to Metformin and that one does seem to help people lose weight. I originally had a reaction to the Metformin in just 24 hours of taking it for the first time. My Dr switched me to Actos. I recently asked if I couldn't try Metformin again now that my BG levels are under control and making sure I eat before taking it. It's working well for me and I have lost a bit of weight with the switch.
Q: How do pornstar actos get their erections so stiff and firm that it stands up straight?
I want to know if its normal for those guys to have their penises that stiff or do they get some special treatmeant? Because when I get an erection, my penis gets hard, but doesn't stand up like those pornstar actors.
These guys have their penises stand straight up, and I want to know if there's a possible way for me to get it like that too. Because almost every porn actor has a crazy erection. I want to get mine like that.
Is that normal for most or all men, are is it just me?
If there's a way to get the penis like that, and anyone knows, please do let me know. Thank you.
A: They aren't really men, they are women wearing strap-ons.
Q: What is the cause of rapid weight gain on ACTOS an anti diabetes medicine?
my mom has been taking it and is know rapidly gaining weight. I heard that congestive heart failure is a caused
A: That medication works by reducing insulin resistance in Type 2 diabetics. Without the med, her body cannot recognize and use the insulin it's making. So it makes more, and more, and more..... Actos works to reduce the insulin levels. But in doing so, it also causes fat formation b/c the insulin has to work on *something*...
Also, and this is where self-control comes in, she's probably not eating a diabetic or ADA diet. She's eating too many calories each day, and now that her insulin levels are normal, she's packing on the weight.
It's a double-edged sword, but she needs to tell her diabetes doctor she's gaining weight on that medication.
Q: Has anyone else been switched from Metformin to Actos?
I'm type 2 diabetic, taking insulin. I asked my doctor to switch me off Metformin; because I was having severe intestinal gas.
He switched me to Actos, which has stopped the gas problem.
My blood glucose readings have improved markedly; but I have gained weight rapidly in the elapsed month.
My feeling is that this is due to increased water retention.
Have others experienced similar side-effects?
What did you do about it?
A: best to see gp about this one, metformin is drug of choice as in the gold standard or first line treatment, its proven to cause weight lost in type two, whereas actos weight neutral and studies have shown it to have cardiovascular sideffects such as heart failure which a symptom is water retention and heart attacks etc
best bet make appointment see Gp
Q: Has anyone taken Actos?What are your thoughts on this med?
what is ED?
I've been on it now few months and have swelling /weight gain.
Has anyone had any other side effects?
A: I've taken Actos now for about 7yrs.I did see a difference in my blood sugar after about 2 mons.It
got easier to control. Now, it's getting a little harder to control.
Recently,though I've heard so much about the dangers, "THE BLACK LABEL" Warnings which are now on my prescription bottles I have decided
to talk with my doctor about taking me off.I don't want to wait until damage is done(if not already)or it kills me before they take it off the market.
It can cause Congestive Heart Failure,Stroke& Heart Attacks in some people. I just don't want to be one of "Them" before they decided.
Q: Diabetes type 2, taking Metformin near 1 year but now stop due to feeling tired, can I take Actos instead of?
Metformin, Thanks?
A: Actos and Metformin act differently in the body. The best person to advise you on changing your presciption medication would be the healthcare professional that prescribed it for you.
Let you doc or NP know the problems you are having, and be willing to listen to suggestions.
Q: theorist who have theories on random acts of violence or actos of violence?
I have a project which is due on monday and is worth 15% of my mark....One part of it is to include theorist who have theories on random acts of violence or violence acts.
Thanks!
A: You should look Schadenfreude. It's originally a German term (though now used in English too) coined by Theodor Adorno. He defined it as, “largely unanticipated delight in the suffering of another which is cognized as trivial and/or appropriate.” He used the term to describe why so many ordinary German seemed to take pleasure in all of the ills that befell the Jews during the holocaust.
There's been some psychological studies investigating its causes. For example, this paper in Nature (http://www.nature.com/doifinder/10.1038/nature04271) found that when men perceive someone as deserving punishment (like a child rapist in the gas chamber), that they actually took pleasure in that person's suffering.
Also, this paper in Nature suggests that Schadenfreude is linked up to envy, namely that when someone has something you want and they lose it, or get hurt in some other way, that we feel good about it, http://www.sciencemag.org/cgi/content/abstract/323/5916/937.